Startup File

Reference

Mode: All modes
Menu: File ‣ Save Startup File
Hotkey: Ctrl-U

Saves the current file as the default Blender file startup.blend. This file is loaded every time Blender is opened or a new file is generated (File ‣ New).

It contains the default startup scene included with Blender. This startup scene can be replaced by your own customized setup.

To change the startup scene, make all of the desired changes to the current scene or current file and File ‣ Save Startup File.

Saving the startup.blend still stores user preferences in the file. Only if a userpref.blend exists, it uses the preferences from that file.

(ToDo add): Restore Load Factory Settings.